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105784-83-6

  • Product Name：5-IODO-2',3'-DIDEOXYURIDINE
  • Molecular Formula：C9H11 I N2 O4
  • Purity：99%
  • Molecular Weight：338.102
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Product Details;

CasNo： 105784-83-6

Molecular Formula： C9H11 I N2 O4

USP In Bulk Supply 5-IODO-2',3'-DIDEOXYURIDINE 105784-83-6 Powder

  • Molecular Formula:C9H11 I N2 O4
  • Molecular Weight:338.102
  • Melting Point:176 °C (dec.)(lit.)
     
  • Boiling Point:°Cat760mmHg 
  • PKA:7.94±0.10(Predicted) 
  • Flash Point:°C 
  • PSA：84.32000 
  • Density:2.02g/cm3 
  • LogP:-0.18890 

105784-83-6 Relevant articles

Inhibition of Mycobacterium tuberculosis, Mycobacterium bovis, and Mycobacterium avium by novel dideoxy nucleosides

Rai, Dinesh,Johar, Monika,Srivastav, Naveen C.,Manning, Tracey,Agrawal,Kunimoto, Dennis Y.,Kumar, Rakesh

, p. 4766 - 4774 (2008/03/12)

The prevalence of tuberculosis (TB) and ...

Discovery of a New Family of Inhibitors of Human Cytomegalovirus (HCMV) Based upon Lipophilic Alkyl Furano Pyrimidine Dideoxy Nucleosides: Action via a Novel Non-Nucleosidic Mechanism

McGuigan, Christopher,Pathirana, Ranjith N.,Snoeck, Robert,Andrei, Graciela,De Clercq, Erik,Balzarini, Jan

, p. 1847 - 1851 (2007/10/03)

Following our discovery of the potent an...

Cyanine dye activating group with improved coupling selectivity

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, (2008/06/13)

Activating groups for cyanine dyes used ...

Alkynylamino-nucleotides

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, (2008/06/13)

Alkynylamino-nucleotides and labeled alk...

105784-83-6 Process route

2',3'-Dideoxyuridine
5983-09-5,153547-98-9

2',3'-Dideoxyuridine

5-Iodo-2',3'-dideoxyuridine
105784-83-6

5-Iodo-2',3'-dideoxyuridine

Conditions
Conditions Yield
With sodium azide; Iodine monochloride; In acetonitrile; at 25 ℃; for 24h;
87%
2',3'-Dideoxyuridine; With Iodine monochloride; In methanol; at 20 ℃; for 2h;
With ammonium hydroxide; In methanol;
70%
With iodine; silver nitrate; In methanol;
51.4%
With Iodine monochloride; In methanol;
Multi-step reaction with 2 steps
1: iodine monochloride / 0.17 h / 20 °C
2: 80 percent / triethylamine / acetonitrile / 2 h / Heating
With Iodine monochloride; triethylamine; In acetonitrile;
With Iodine monochloride; In methanol;
2.232 g (66%)
With Iodine monochloride; In methanol;
2.232 g (66%)
With Iodine monochloride; In methanol;
2.232 g (66%)
2',3'-Dideoxyuridine
5983-09-5

2',3'-Dideoxyuridine

2',3'-dideoxy-5-iodouridine
105784-83-6

2',3'-dideoxy-5-iodouridine

Conditions
Conditions Yield
With iodine; iodic acid; In tetrachloromethane; water; acetic acid; at 45 ℃; for 2h;
31%

105784-83-6 Upstream products

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    2'-deoxyuridine

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105784-83-6 Downstream products

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    5-(3-Trifluoroacetamido-1-propynyl)-2',3'-dideoxy-uridine

  • 1393815-12-7
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    3'-O-acetyl-5-(2-(4-ethynylphenyl)ethynyl)-2'-deoxycytidine

  • 1393815-10-5
    1393815-10-5

    3'-O-acetyl-5-(2-(4-ethynylphenyl)ethynyl)-2'-deoxyuridine

  • 114748-60-6
    114748-60-6

    2,2,2-Trifluoro-N-{3-[1-((S)-5-hydroxymethyl-tetrahydro-furan-2-yl)-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl]-prop-2-ynyl}-acetamide

CAS Index: 1 2 3 4 5 6 7 8 9

Chemical Name Index: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

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