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121058-82-0

  • Product Name:5'-DMT-Ac-rC
  • Molecular Formula:C32H33 N3 O8
  • Purity:99%
  • Molecular Weight:587.629
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Product Details;

CasNo: 121058-82-0

Molecular Formula: C32H33 N3 O8

High Quality For Sale 5'-DMT-Ac-rC 121058-82-0 In Stock

  • Molecular Formula:C32H33 N3 O8
  • Molecular Weight:587.629
  • PKA:10.21±0.20(Predicted) 
  • PSA:141.37000 
  • Density:1.32±0.1 g/cm3(Predicted) 
  • LogP:2.91980 

121058-82-0 Relevant articles

Methylamine Deprotection Provides Increased Yield of Oligoribonucleotides

Reddy, M. P.,Farooqui, Firdous,Hanna, Naeem B.

, p. 8929 - 8932 (1995)

Use of methylamine or methylamine/ammoni...

UNA (unlocked nucleic acid): A flexible RNA mimic that allows engineering of nucleic acid duplex stability

Langkjaer, Niels,Pasternak, Anna,Wengel, Jesper

experimental part, p. 5420 - 5425 (2009/12/06)

UNA (unlocked nucleic acid) monomers are...

A base-labile group for 2′-OH protection of ribonucleosides: A major challenge for RNA synthesis

Lavergne, Thomas,Bertrand, Jean-Remi,Vasseur, Jean-Jacques,Debart, Francoise

scheme or table, p. 9135 - 9138 (2009/10/01)

A base-labile group for 2'-OH protection...

A new RNA synthetic method with a 2′-O-(2-cyanoethoxymethyl) protecting group

Ohgi, Tadaaki,Masutomi, Yutaka,Ishiyama, Kouichi,Kitagawa, Hidetoshi,Shiba, Yoshinobu,Yano, Junichi

, p. 3477 - 3480 (2007/10/03)

(Chemical Equation Presented) A novel me...

Synthesis of a new transition-state analog of the sialyl donor. Inhibition of sialyltransferases

Sun, Hongbin,Yang, Jingsong,Amaral, Katie E.,Horenstein, Benjamin A.

, p. 2451 - 2453 (2007/10/03)

A new class of glycosyltransferase inhib...

121058-82-0 Process route

4,4'-dimethoxytrityl chloride
40615-36-9

4,4'-dimethoxytrityl chloride

N-acetylcytidine
3768-18-1

N-acetylcytidine

N<sup>4</sup>-acetyl-5'-O-(4,4'-dimethoxytrityl)cytidine
121058-82-0

N4-acetyl-5'-O-(4,4'-dimethoxytrityl)cytidine

Conditions
Conditions Yield
In pyridine; at 5 ℃; for 20h;
65%
With pyridine; at 25 ℃;
61%
In pyridine; at 5 ℃;
With pyridine;
With pyridine; at 20 ℃;
With pyridine; at 20 ℃; for 2h; Inert atmosphere;
4,4'-dimethoxytrityl chloride
40615-36-9

4,4'-dimethoxytrityl chloride

acetic anhydride
108-24-7

acetic anhydride

CYTIDINE
65-46-3

CYTIDINE

N<sup>4</sup>-acetyl-5'-O-(4,4'-dimethoxytrityl)cytidine
121058-82-0

N4-acetyl-5'-O-(4,4'-dimethoxytrityl)cytidine

Conditions
Conditions Yield
acetic anhydride; CYTIDINE; In N,N-dimethyl-formamide; at 20 ℃; for 14h;
4,4'-dimethoxytrityl chloride; With pyridine; In N,N-dimethyl-formamide; at 20 ℃; for 1h;
70%

121058-82-0 Upstream products

  • 40615-36-9
    40615-36-9

    4,4'-dimethoxytrityl chloride

  • 3768-18-1
    3768-18-1

    N-acetylcytidine

  • 108-24-7
    108-24-7

    acetic anhydride

  • 65-46-3
    65-46-3

    CYTIDINE

121058-82-0 Downstream products

  • 121058-85-3
    121058-85-3

    5'-O-DMTr-2'-O-TBDMS-N4-acetylcytidine

  • 123956-65-0
    123956-65-0

    N-{1-[(2R,3R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-tetrahydro-furan-2-yl]-2-oxo-1,2-dihydro-pyrimidin-4-yl}-acetamide

  • 231957-28-1
    231957-28-1

    N-{1-[(2R,3R,4R,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-3-(2-nitro-benzyloxymethoxy)-tetrahydro-furan-2-yl]-2-oxo-1,2-dihydro-pyrimidin-4-yl}-acetamide

  • 253586-21-9
    253586-21-9

    N4-acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-{[(triisopropylsilyl)oxy]methyl}cytidine

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