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151390-97-5

  • Product Name:2'-O-Propargyladenosine
  • Molecular Formula:C13H15N5O4
  • Purity:99%
  • Molecular Weight:305.293
Inquiry

Product Details;

CasNo: 151390-97-5

Molecular Formula: C13H15N5O4

In Medicine Good Producer 2'-O-Propargyladenosine 151390-97-5 In Bulk Supply

  • Molecular Formula:C13H15N5O4
  • Molecular Weight:305.293
  • Boiling Point:655.1±65.0 °C(Predicted) 
  • PKA:13.00±0.70(Predicted) 
  • PSA:128.54000 
  • Density:1.65±0.1 g/cm3(Predicted) 
  • LogP:-0.74130 

151390-97-5 Relevant articles

CLASS A GPCR-BINDING COMPOUND MODIFIER

-

Paragraph 0203; 0223-0224, (2020/07/14)

To provide a novel class-A GPCR antagoni...

Synthesis and incorporation of a furan-modified adenosine building block for DNA interstrand crosslinking

Jawalekar, Anup M.,Op De Beeck, Marieke,Van Delft, Floris L.,Madder, Annemieke

supporting information; experimental part, p. 2796 - 2798 (2011/05/05)

2′-O-(3-(Furan-2-yl)propyl)adenosine was...

151390-97-5 Process route

propargyl bromide
106-96-7

propargyl bromide

adenosine
58-61-7

adenosine

2'-O-(1-propyn-3-yl)adenosine
151390-97-5

2'-O-(1-propyn-3-yl)adenosine

Conditions
Conditions Yield
adenosine; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 5 - 50 ℃; Inert atmosphere;
propargyl bromide; With tetra-(n-butyl)ammonium iodide; In N,N-dimethyl-formamide; mineral oil; at 55 ℃; for 48h; Inert atmosphere;
45%
adenosine; With sodium hydride; In N,N-dimethyl-formamide; at 0 - 50 ℃; for 0.25h; Inert atmosphere;
propargyl bromide; With tetra-(n-butyl)ammonium iodide; In N,N-dimethyl-formamide; at 55 ℃; Inert atmosphere;
10%
2'-O-(1-propyn-3-yl)adenosine
151390-97-5

2'-O-(1-propyn-3-yl)adenosine

C<sub>12</sub>H<sub>15</sub>N<sub>5</sub>O<sub>2</sub>

C12H15N5O2

C<sub>25</sub>H<sub>30</sub>N<sub>10</sub>O<sub>6</sub>

C25H30N10O6

Conditions
Conditions Yield
With copper(ll) sulfate pentahydrate; sodium L-ascorbate; In tetrahydrofuran; water; tert-butyl alcohol; at 20 ℃; for 4h; Inert atmosphere;
66%

151390-97-5 Upstream products

  • 106-96-7
    106-96-7

    propargyl bromide

  • 58-61-7
    58-61-7

    adenosine

151390-97-5 Downstream products

  • 1282033-18-4
    1282033-18-4

    2'-O-(3-(furan-2-yl)-propyn-3-yl)-6-N-benzoyladenosine

  • 1282033-19-5
    1282033-19-5

    2'-O-(3-(furan-2-yl)-propyl)-6-N-benzoyladenosine

  • 1282033-20-8
    1282033-20-8

    5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(3-(furan-2-yl)-propyl)-6-N-benzoyladenosine

  • 1282033-21-9
    1282033-21-9

    5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(3-(furan-2-yl)-propyl)-6-N-benzoyladenosine-3'-O-(2-cyanoethyl N, N-diisopropylphosphoramidite)

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