What is the 5'-O-DMT-N2-Isobutyryl-2'-O-methyl-D-guanosine?

5'-O-DMT-N2-Isobutyryl-2'-O-methyl-D-guanosine is , while it's Molecular Formula is C36H39 N5 O8. 5''-O-DMT-N2-Isobutyryl-2''-O-methyl-D-guanosine (CAS# 114745-26-5) is a guanosine derivative used in the preparation of synthetic RNA derivatives such as native-like crosslinked duplex RNA for use in biochemical and nanotechnology studies.

What is the CAS number for 5'-O-DMT-N2-Isobutyryl-2'-O-methyl-D-guanosine?

The CAS number of 5'-O-DMT-N2-Isobutyryl-2'-O-methyl-D-guanosine is 114745-26-5.

What is the 5'-O-DMT-N2-Isobutyryl-2'-O-methyl-D-guanosine?

5'-O-DMT-N2-Isobutyryl-2'-O-methyl-D-guanosine is , while it's Molecular Formula is C36H39 N5 O8. 5''-O-DMT-N2-Isobutyryl-2''-O-methyl-D-guanosine (CAS# 114745-26-5) is a guanosine derivative used in the preparation of synthetic RNA derivatives such as native-like crosslinked duplex RNA for use in biochemical and nanotechnology studies.

What is the CAS number for 5'-O-DMT-N2-Isobutyryl-2'-O-methyl-D-guanosine?

The CAS number of 5'-O-DMT-N2-Isobutyryl-2'-O-methyl-D-guanosine is 114745-26-5.

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114745-26-5

Q: What is 5'-O-DMT-N2-Isobutyryl-2'-O-methyl-D-guanosine (114745-26-5) used for?

5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine is a nucleoside that is made using an oxime opening of the 5' position and a methylation at the 2' position. 5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine has been shown to have an affinity for tissues in a chemotactic assay.

Product Name：5'-O-DMT-N2-Isobutyryl-2'-O-methyl-D-guanosine
Molecular Formula：C36H39 N5 O8
Purity：99%
Molecular Weight：669.734

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Product Details;

CasNo： 114745-26-5

Molecular Formula： C36H39 N5 O8

Fast Delivery High Purity 5'-O-DMT-N2-Isobutyryl-2'-O-methyl-D-guanosine 114745-26-5 In Stock

Molecular Formula:C36H39 N5 O8
Molecular Weight:669.734
PKA:9.16±0.20(Predicted)
PSA：159.05000
Density:1.35±0.1 g/cm3(Predicted)
LogP:4.08630

114745-26-5 Relevant articles

An efficient multigram synthesis of monomers for the preparation of novel oligonucleotides containing isosteric non-phosphorous backbones

Dimock, Stuart,Bhat, Balkrishen,Peoc'h, Didier,Sanghvi, Yogesh S.,Swayze, Eric E.

, p. 1629 - 1632 (2007/10/03)

The facile preparation of two novel clas...

Oligo(2′-O-methylribonucleotides) and their derivatives. II. Synthesis and properties of oligo(2′-O-methylribonucleotides) modified with N-(2-hydroxyethyl)phenazinium and steroid groups at the 5′-terminus

Sergeeva,Lokhov,Ven'yaminova

, p. 800 - 806 (2007/10/03)

Oligo(2′-O-methylribonucleotides) modifi...

114745-26-5 Process route

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 81246-83-5
9-(5-O-dimethoxytrityl-β-D-ribofuranosyl)-2-N-isobutyrylguanine

: N-(9-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide

: 114745-26-5
N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide

Conditions

Conditions	Yield
With tin(ll) chloride; In N,N-dimethyl-formamide; at 0 ℃; for 1h;	40%

: 63264-29-9
N²-isobutyryl-2′-O-methylguanosine

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 114745-26-5
N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide

Conditions

Conditions	Yield
With pyridine; at 0 - 20 ℃; for 18h; Yield given;

114745-26-5 Upstream products

186581-53-3
diazomethane
81246-83-5
9-(5-O-dimethoxytrityl-β-D-ribofuranosyl)-2-N-isobutyrylguanine
63264-29-9
N²-isobutyryl-2′-O-methylguanosine
40615-36-9
4,4'-dimethoxytrityl chloride

114745-26-5 Downstream products

199581-46-9
Thiocarbonic acid O-[(2R,3R,4R,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(2-isobutyrylamino-6-oxo-1,6-dihydro-purin-9-yl)-4-methoxy-tetrahydro-furan-3-yl] ester O-(3-tert-butyl-phenyl) ester
198703-58-1
N-(9-{(2R,3R,4R,5S)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-formyl-3-methoxy-tetrahydro-furan-2-yl}-6-oxo-6,9-dihydro-1H-purin-2-yl)-isobutyramide
880260-29-7
C₄₂H₅₃N₅O₈Si
1058150-81-4
O-(N₄,2',3'-O,O-tribenzoylcytidin-5'-yl)-O-[N₂-isobutyryl-2'-O-methyl-5'-O-(4,4'-dimethoxytrityl)guanosin-3'-yl] hydrogenophosphonate diester

Product Classification

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114745-26-5

Product Details;

Fast Delivery High Purity 5'-O-DMT-N2-Isobutyryl-2'-O-methyl-D-guanosine 114745-26-5 In Stock

114745-26-5 Relevant articles

An efficient multigram synthesis of monomers for the preparation of novel oligonucleotides containing isosteric non-phosphorous backbones

Dimock, Stuart,Bhat, Balkrishen,Peoc'h, Didier,Sanghvi, Yogesh S.,Swayze, Eric E.

, p. 1629 - 1632 (2007/10/03)

Oligo(2′-O-methylribonucleotides) and their derivatives. II. Synthesis and properties of oligo(2′-O-methylribonucleotides) modified with N-(2-hydroxyethyl)phenazinium and steroid groups at the 5′-terminus

Sergeeva,Lokhov,Ven'yaminova

, p. 800 - 806 (2007/10/03)

114745-26-5 Process route

114745-26-5 Upstream products

114745-26-5 Downstream products

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