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197850-75-2

  • Product Name:6-Carboxyfluorescein Dipivalate NHS Ester
  • Molecular Formula:C35H31NO11
  • Purity:99%
  • Molecular Weight:641.631
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Product Details;

CasNo: 197850-75-2

Molecular Formula: C35H31NO11

High Quality Good Producer 6-Carboxyfluorescein Dipivalate NHS Ester 197850-75-2 In Stock

  • Molecular Formula:C35H31NO11
  • Molecular Weight:641.631
  • PSA:151.81000 
  • LogP:5.31630 

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197850-75-2 Process route

1-hydroxy-pyrrolidine-2,5-dione
6066-82-6

1-hydroxy-pyrrolidine-2,5-dione

3',6'-bis(2,2-dimethyl-1-oxopropoxy)-3-oxo-spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylic acid
192374-17-7

3',6'-bis(2,2-dimethyl-1-oxopropoxy)-3-oxo-spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylic acid

1-{[(3,6-di-O-pivaloyl)fluorescein-6-yl]oxy}pyrrolidine-2,5-dione
197850-75-2

1-{[(3,6-di-O-pivaloyl)fluorescein-6-yl]oxy}pyrrolidine-2,5-dione

Conditions
Conditions Yield
With N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In various solvent(s);
With dicyclohexyl-carbodiimide; In 1,4-dioxane; for 0.416667h; Inert atmosphere;
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 0.5h; Inert atmosphere; Schlenk technique;
0.64 g
2,2-dimethylpropanoic anhydride
1538-75-6

2,2-dimethylpropanoic anhydride

1-{[(3,6-di-O-pivaloyl)fluorescein-6-yl]oxy}pyrrolidine-2,5-dione
197850-75-2

1-{[(3,6-di-O-pivaloyl)fluorescein-6-yl]oxy}pyrrolidine-2,5-dione

Conditions
Conditions Yield
Multi-step reaction with 2 steps
1: DIPEA / dimethylformamide; various solvent(s) / 72 h / 20 °C
2: EDC / various solvent(s)
With N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; 1: Esterification / 2: Esterification;

197850-75-2 Upstream products

  • 6066-82-6
    6066-82-6

    1-hydroxy-pyrrolidine-2,5-dione

  • 192374-17-7
    192374-17-7

    3',6'-bis(2,2-dimethyl-1-oxopropoxy)-3-oxo-spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylic acid

  • 1538-75-6
    1538-75-6

    2,2-dimethylpropanoic anhydride

  • 3301-79-9
    3301-79-9

    6-carboxyfluorescein

197850-75-2 Downstream products

  • 866824-20-6
    866824-20-6

    N-(3',6'-dipivaloylfluorescein-6-ylcarbonyl)-3'-amino-3'-deoxythymidine

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