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251647-48-0

  • Product Name:5'-O-DMT-2'-O-MOE-N6-Bz-rA
  • Molecular Formula:C41H41N5O8
  • Purity:99%
  • Molecular Weight:731.805
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Product Details;

CasNo: 251647-48-0

Molecular Formula: C41H41N5O8

Factory Sells Reliable Quality For Sale 5'-O-DMT-2'-O-MOE-N6-Bz-rA 251647-48-0

  • Molecular Formula:C41H41N5O8
  • Molecular Weight:731.805
  • PKA:7.87±0.43(Predicted) 
  • PSA:151.80000 
  • Density:1.31 
  • LogP:5.77840 

251647-48-0 Relevant articles

Copper(II)nitrate catalyzed regioselective protection of primary alcohols with 4,4′-dimethoxytrityl and 2,7-dimethyl-9-phenyl xanthen-9-yl groups in nucleosides and carbohydrates

Penjarla, Srishylam,Prasad, S. Rajendra,Reddy, Dhande Sudhakar,Banerjee, Shyamapada,Penta, Santhosh,Sanghvi, Yogesh S.

, p. 232 - 247 (2018/05/14)

Regioselective protection of primary hyd...

Synthesis and cellular activity of stereochemically-pure 2′-O-(2-methoxyethyl)-phosphorothioate oligonucleotides

Li,Lightfoot,Halloy,Malinowska,Berk,Behera,Schümperli,Hall

supporting information, p. 541 - 544 (2017/01/13)

Stereochemically-pure 2′-O-(2-methoxyeth...

2'-O-MOE-3'-H-phosphorothioate nucleoside monomer and synthetic method thereof

-

Paragraph 0044; 0045, (2017/01/23)

The invention discloses 2'-O-MOE-3'-H-ph...

251647-48-0 Process route

4,4'-dimethoxytrityl chloride
40615-36-9

4,4'-dimethoxytrityl chloride

2'-O-methoxyethyl- N<SUP>6</SUP>-benzoyl -adenosine
333335-93-6

2'-O-methoxyethyl- N6-benzoyl -adenosine

5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-N6-benzoyladenosine
251647-48-0

5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-N6-benzoyladenosine

Conditions
Conditions Yield
2'-O-methoxyethyl- N6-benzoyl -adenosine; With pyridine; at 20 ℃; for 0.5h; Inert atmosphere;
4,4'-dimethoxytrityl chloride; for 4h;
86.1%
With pyridine; In methanol; at 0 ℃; for 3.5h;
81%
4,4'-dimethoxytrityl alcohol
40615-35-8

4,4'-dimethoxytrityl alcohol

2'-O-methoxyethyl- N<SUP>6</SUP>-benzoyl -adenosine
333335-93-6

2'-O-methoxyethyl- N6-benzoyl -adenosine

5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-N6-benzoyladenosine
251647-48-0

5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-N6-benzoyladenosine

Conditions
Conditions Yield
With copper(II) nitrate; In dichloromethane; for 6h; Reagent/catalyst; Reflux;
30%

251647-48-0 Upstream products

  • 40615-36-9
    40615-36-9

    4,4'-dimethoxytrityl chloride

  • 333335-93-6
    333335-93-6

    2'-O-methoxyethyl- N6-benzoyl -adenosine

  • 58-61-7
    58-61-7

    adenosine

  • 168427-74-5
    168427-74-5

    2'-O-(2-methoxyethyl)adenosine

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