What is the 5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYADENOSINE?

5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYADENOSINE is , while it's Molecular Formula is C31H31 N5 O5. 5''-O-(4,4''-dimethoxytrityl)-2''-deoxyadenosine (CAS# 17331-22-5) is a nucleoside used to synthesize oligonucleotides for triazole- and tetrazole-?bridged nucleic acids.

What is the CAS number for 5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYADENOSINE?

The CAS number of 5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYADENOSINE is 17331-22-5.

What is the 5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYADENOSINE?

5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYADENOSINE is , while it's Molecular Formula is C31H31 N5 O5. 5''-O-(4,4''-dimethoxytrityl)-2''-deoxyadenosine (CAS# 17331-22-5) is a nucleoside used to synthesize oligonucleotides for triazole- and tetrazole-?bridged nucleic acids.

What is the CAS number for 5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYADENOSINE?

The CAS number of 5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYADENOSINE is 17331-22-5.

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17331-22-5

Product Name：5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYADENOSINE
Molecular Formula：C31H31 N5 O5
Purity：99%
Molecular Weight：553.618

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Product Details;

CasNo： 17331-22-5

Molecular Formula： C31H31 N5 O5

Good Price Factory Sells High Purity 5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYADENOSINE 17331-22-5

Molecular Formula:C31H31 N5 O5
Molecular Weight:553.618
Melting Point:97-98 °C(Solv: chloroform (67-66-3); ligroine (8032-32-4))
Boiling Point:785.1±70.0 °C(Predicted)
PKA:13.75±0.60(Predicted)
PSA：126.77000
Density:1.35±0.1 g/cm3(Predicted)
LogP:4.66400

17331-22-5 Relevant articles

Transient Protection: Efficient One-Flask Syntheses of Protected Deoxynucleosides

Ti, G. S.,Gaffney, B. L.,Jones, R. A.

, p. 1316 - 1319 (1982)

Application of the concept of transient ...

A Convenient Method for the Synthesis of N-Free 5′-O-(p,p′-Dimethoxytrityl)-2′-deoxyribonucleosides via the 5′-O-Selective Tritylation of the Parent Substances

Kataoka, Masanori,Hayakawa, Yoshihiro

, p. 6087 - 6089 (1999)

Characterization of high molecular weight impurities in synthetic phosphorothioate oligonucleotides

Kurata, Christine,Bradley, Kym,Gaus, Hans,Luu, Nhuy,Cedillo, Isaiah,Ravikumar, Vasulinga T.,Sooy, Kent Van,McArdle, James V.,Capaldi, Daniel C.

, p. 607 - 614 (2006)

Phosphorothioate oligonucleotides manufa...

MODIFIED NUCLEOTIDES FOR SYNTHESIS OF NUCLEIC ACIDS, A KIT CONTAINING SUCH NUCLEOTIDES AND THEIR USE FOR THE PRODUCTION OF SYNTHETIC NUCLEIC ACID SEQUENCES OR GENES

-

Paragraph 0118, (2020/08/05)

A modified nucleotide, intended for the ...

Conversion of adenine to 5-amino-4-pyrimidinylimidazole caused by acetyl capping during solid phase oligonucleotide synthesis

Rodriguez, Andrew A.,Cedillo, Isaiah,McPherson, Andrew K.

, p. 3468 - 3471 (2016/07/21)

The acetyl capping reaction used through...

Synthesis of disaccharide nucleosides by the O-glycosylation of natural nucleosides with thioglycoside donors

Aoki, Shin,Fukumoto, Taketo,Itoh, Taiki,Kurihara, Masayuki,Saito, Shigeto,Komabiki, Shin-Ya

, p. 740 - 751 (2015/06/02)

Disaccharide nucleosides constitute an i...

17331-22-5 Process route

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 958-09-8,7005-15-4
2'-deoxy-D-adenosine

: 17331-22-5
5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxyadenosine

Conditions

Conditions	Yield
With 1H-imidazole; methanesulfonic acid; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 2h;	86%
With pyridine; dmap; triethylamine; for 4h;	77%
With pyridine; at 0 - 20 ℃;	68%
With pyridine; dmap; triethylamine; at 13 ℃; for 12h;

4,4'-dimethoxytrityl chloride; 2'-deoxy-D-adenosine; With pyridine; dmap; triethylamine; at 20 ℃; With methanesulfonyl chloride; triethylamine; at 20 ℃; for 2h;

: 329781-61-5
2-azidomethyl-N-(9-{5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-9H-purin-6-yl)-benzamide

: 17331-22-5
5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxyadenosine

Conditions

Conditions	Yield
With diphenyl(methyl)phosphine; In 1,4-dioxane; water; at 20 ℃; for 0.333333h;	90%

17331-22-5 Upstream products

40615-36-9
4,4'-dimethoxytrityl chloride
958-09-8
2'-deoxy-D-adenosine
187674-19-7
(9-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-9H-purin-6-yl)-carbamic acid 2-(5-dimethylamino-naphthalene-1-sulfonyl)-ethyl ester
84780-16-5
2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-N⁶-phthaloyladenosine

17331-22-5 Downstream products

112677-85-7
Phosphoric acid diallyl ester (2R,3S,5R)-5-(6-amino-purin-9-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-3-yl ester
134817-00-8
Diisopropyl-phosphoramidous acid (2R,3S,5R)-5-(6-amino-purin-9-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-3-yl ester methyl ester
89947-86-4
5'-O-(4,4'-dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)-2'-deoxyadenosine
958-09-8
2'-deoxy-D-adenosine

Product Classification

Contact us

17331-22-5

Product Details;

Good Price Factory Sells High Purity 5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYADENOSINE 17331-22-5

17331-22-5 Relevant articles

Transient Protection: Efficient One-Flask Syntheses of Protected Deoxynucleosides

Ti, G. S.,Gaffney, B. L.,Jones, R. A.

, p. 1316 - 1319 (1982)

A Convenient Method for the Synthesis of N-Free 5′-O-(p,p′-Dimethoxytrityl)-2′-deoxyribonucleosides via the 5′-O-Selective Tritylation of the Parent Substances

Kataoka, Masanori,Hayakawa, Yoshihiro

, p. 6087 - 6089 (1999)

Characterization of high molecular weight impurities in synthetic phosphorothioate oligonucleotides

Kurata, Christine,Bradley, Kym,Gaus, Hans,Luu, Nhuy,Cedillo, Isaiah,Ravikumar, Vasulinga T.,Sooy, Kent Van,McArdle, James V.,Capaldi, Daniel C.

, p. 607 - 614 (2006)

MODIFIED NUCLEOTIDES FOR SYNTHESIS OF NUCLEIC ACIDS, A KIT CONTAINING SUCH NUCLEOTIDES AND THEIR USE FOR THE PRODUCTION OF SYNTHETIC NUCLEIC ACID SEQUENCES OR GENES

-

Paragraph 0118, (2020/08/05)

Conversion of adenine to 5-amino-4-pyrimidinylimidazole caused by acetyl capping during solid phase oligonucleotide synthesis

Rodriguez, Andrew A.,Cedillo, Isaiah,McPherson, Andrew K.

, p. 3468 - 3471 (2016/07/21)

Synthesis of disaccharide nucleosides by the O-glycosylation of natural nucleosides with thioglycoside donors

Aoki, Shin,Fukumoto, Taketo,Itoh, Taiki,Kurihara, Masayuki,Saito, Shigeto,Komabiki, Shin-Ya

, p. 740 - 751 (2015/06/02)

17331-22-5 Process route

17331-22-5 Upstream products

17331-22-5 Downstream products

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