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223777-15-9

  • Product Name:2'-O-(2-Methoxyethyl)-uridine
  • Molecular Formula:C12H18N2O7
  • Purity:99%
  • Molecular Weight:302.284
Inquiry

Product Details;

CasNo: 223777-15-9

Molecular Formula: C12H18N2O7

Low Price Crystalline Powder Food Grade 2'-O-(2-Methoxyethyl)-uridine 223777-15-9

  • Molecular Formula:C12H18N2O7
  • Molecular Weight:302.284
  • Refractive Index:1.586 
  • PKA:9.39±0.10(Predicted) 
  • PSA:123.01000 
  • Density:1.461 g/cm3 
  • LogP:-2.18120 

2'-O-(2-Methoxyethyl)uridine(Cas 223777-15-9) Usage

Uses

A uridine derivative as building blocks for cross-linking oligonucleotides.

InChI:InChI=1/C12H18N2O7/c1-19-4-5-20-10-9(17)7(6-15)21-11(10)14-3-2-8(16)13-12(14)18/h2-3,7,9-11,15,17H,4-6H2,1H3,(H,13,16,18)/t7-,9+,10+,11-/m1/s1

223777-15-9 Relevant articles

Conversion of uridine into 2'-O-(2-methoxyethyl)uridine and 2'-O-(2- methoxyethyl)cytidine

Legorburu, Urtzi,Reese, Colin B.,Song, Quanlai

, p. 5635 - 5640 (1999)

Reaction between aluminium 2-methoxyetho...

NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF

-

Paragraph 0465, (2019/04/27)

Disclosed herein are compositions and ph...

2′-Substituted RNA preparation

-

, (2008/06/13)

A process for the preparation of a compo...

2'-SUBSTITUTED RNA PREPARATION

-

Page 5, (2010/11/30)

A process for the preparation of a compo...

223777-15-9 Process route

2-methoxy-ethanol
109-86-4,95507-80-5

2-methoxy-ethanol

2,2'-Anhydrouridine
3736-77-4

2,2'-Anhydrouridine

2'-O-(2-methoxyethyl)uridine
223777-15-9

2'-O-(2-methoxyethyl)uridine

Conditions
Conditions Yield
With aluminium; for 48h; Heating;
91%
2-methoxy-ethanol; With aluminium; for 1h; Heating / reflux;
2,2'-Anhydrouridine; for 48h; Heating / reflux;
In ethanol; water; for 0.166667h; Heating / reflux;
91%
With aluminium; at 130 ℃; for 16h;
56%
uridine
58-96-8

uridine

2'-O-(2-methoxyethyl)uridine
223777-15-9

2'-O-(2-methoxyethyl)uridine

Conditions
Conditions Yield
Multi-step reaction with 2 steps
1: 11.31 g / diphenyl carbonate; sodium hydrogen carbonate / N,N-dimethyl-acetamide / 5 h / 100 °C
2: 91 percent / aluminium / 48 h / Heating
With bis(phenyl) carbonate; sodium hydrogencarbonate; aluminium; In N,N-dimethyl acetamide; 1: Dehydration / 2: Etherification;

223777-15-9 Upstream products

  • 109-86-4
    109-86-4

    2-methoxy-ethanol

  • 3736-77-4
    3736-77-4

    2,2'-Anhydrouridine

  • 58-96-8
    58-96-8

    uridine

223777-15-9 Downstream products

  • 223777-16-0
    223777-16-0

    2'-O-(2-methoxyethyl)cytidine

  • 647839-19-8
    647839-19-8

    4-(2,6-Dimethyl-phenoxy)-1-[(2R,3R,4R,5R)-4-hydroxy-5-hydroxymethyl-3-(2-methoxy-ethoxy)-tetrahydro-furan-2-yl]-1H-pyrimidine-2-thione

  • 647839-22-3
    647839-22-3

    1-[(2R,3R,4R,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-3-(2-methoxy-ethoxy)-tetrahydro-furan-2-yl]-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one

  • 647839-17-6
    647839-17-6

    1-[4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-3-(2-methoxy-ethoxy)-tetrahydro-furan-2-yl]-4-(2,6-dimethyl-phenoxy)-1H-pyrimidin-2-one

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