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84416-84-2

  • Product Name：5'-O-(4,4'-DIMETHOXYTRITYL)-N2-ISOBUTYRYL-2'-DEOXYGUANOSINE-3'-(METHYL-N,N-DIISOPROPYL)PHOSPHOR
  • Molecular Formula：C42H53 N6 O8 P
  • Purity：99%
  • Molecular Weight：800.88
Inquiry

Product Details;

CasNo： 84416-84-2

Molecular Formula： C42H53 N6 O8 P

Pharmaceutical Intermediates High Purity In Stock 5'-O-(4,4'-DIMETHOXYTRITYL)-N2-ISOBUTYRYL-2'-DEOXYGUANOSINE-3'-(METHYL-N,N-DIISOPROPYL)PHOSPHOR 84416-84-2

  • Molecular Formula:C42H53 N6 O8 P
  • Molecular Weight:800.88
  • PSA：164.88000 
  • LogP:7.47780 

84416-84-2 Relevant articles

Hindered Dialkylamino Nucleoside Phosphite Reagents in the Synthesis of Two DNA 51-Mers

Adams, Steven P.,Kavka, Kamila S.,Wykes, Evan J.,Holder, Sarah B.,Galluppi, Gerald R.

, p. 661 - 663 (2007/10/02)

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84416-84-2 Process route

5'-O-dimethoxytrityl-N-isobutyryldeoxyguanosine
68892-41-1

5'-O-dimethoxytrityl-N-isobutyryldeoxyguanosine

N,N-diisopropylmethylphosphonamidic chloride
86030-43-5

N,N-diisopropylmethylphosphonamidic chloride

[5'-O-(4,4'-dimethoxytrityl)-N<sub>2</sub>-isobutyryl-2'-deoxyguanosine-3'-yl]-(N,N'-diisopropyl)methylphosphoramidite
84416-84-2

[5'-O-(4,4'-dimethoxytrityl)-N2-isobutyryl-2'-deoxyguanosine-3'-yl]-(N,N'-diisopropyl)methylphosphoramidite

Conditions
Conditions Yield
With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; Ambient temperature;
[5'-O-(4,4'-dimethoxytrityl)-N<sub>2</sub>-isobutyryl-2'-deoxyguanosine-3'-yl]-(N,N'-diisopropyl)methylphosphoramidite
84416-84-2

[5'-O-(4,4'-dimethoxytrityl)-N2-isobutyryl-2'-deoxyguanosine-3'-yl]-(N,N'-diisopropyl)methylphosphoramidite

O-(5'-(4,4'-dimethoxytrityl)-2-N-isobutyryl-2'-deoxyguanosin-3'-yl) O-(methyl) H-phosphonothioate

O-(5'-(4,4'-dimethoxytrityl)-2-N-isobutyryl-2'-deoxyguanosin-3'-yl) O-(methyl) H-phosphonothioate

Conditions
Conditions Yield
With 1H-tetrazole; hydrogen sulfide; In dichloromethane; for 1h;
91%

84416-84-2 Upstream products

  • 68892-41-1
    68892-41-1

    5'-O-dimethoxytrityl-N-isobutyryldeoxyguanosine

  • 86030-43-5
    86030-43-5

    N,N-diisopropylmethylphosphonamidic chloride

84416-84-2 Downstream products

  • 1360780-30-8
    1360780-30-8

    methylphenyl N2-isobutyryl-2'-deoxy-5'-O-dimethoxytritylguanosine-3'-monophosphate

  • 1360780-29-5
    1360780-29-5

    phenyl 2'-deoxyguanosine-3'-monophosphate

  • 1360780-31-9
    1360780-31-9

    phenyl-N2-isobutyryl-2'-deoxyguanosine-3'-monophosphate

  • 167147-37-7
    167147-37-7

    C41H42N5O10P

CAS Index: 1 2 3 4 5 6 7 8 9

Chemical Name Index: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

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