What is the N-Benzoyl-2'-deoxy-cytidine?

N-Benzoyl-2'-deoxy-cytidine is white to off-white powder, while it's Molecular Formula is C16H17 N3 O5. white to off-white powder Reactant in the synthesis of 2', 5'-Dideoxycytidines and Other Derivatives of 2'-Deoxycytidine, N-Protected 2?-Deoxyribonucleosides(useful for oligonucleotide synthesis), 3?-, 5?-and 3?, 5?-di-O-crotonyl 2?-deoxynucleoside derivatives.

What is the CAS number for N-Benzoyl-2'-deoxy-cytidine?

The CAS number of N-Benzoyl-2'-deoxy-cytidine is 4836-13-9.

What is the N-Benzoyl-2'-deoxy-cytidine?

N-Benzoyl-2'-deoxy-cytidine is white to off-white powder, while it's Molecular Formula is C16H17 N3 O5. white to off-white powder Reactant in the synthesis of 2', 5'-Dideoxycytidines and Other Derivatives of 2'-Deoxycytidine, N-Protected 2?-Deoxyribonucleosides(useful for oligonucleotide synthesis), 3?-, 5?-and 3?, 5?-di-O-crotonyl 2?-deoxynucleoside derivatives.

What is the CAS number for N-Benzoyl-2'-deoxy-cytidine?

The CAS number of N-Benzoyl-2'-deoxy-cytidine is 4836-13-9.

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4836-13-9

Product Name：N-Benzoyl-2'-deoxy-cytidine
Molecular Formula：C16H17 N3 O5
Purity：99%
Molecular Weight：331.328

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Product Details;

CasNo： 4836-13-9

Molecular Formula： C16H17 N3 O5

Appearance： white to off-white powder

Best Price 4836-13-9 N-Benzoyl-2'-deoxy-cytidine Good Supplier In Chi

Molecular Formula:C16H17 N3 O5
Molecular Weight:331.328
Appearance/Colour:white to off-white powder
Melting Point:215-220 °C (dec.)
Refractive Index:90 ° (C=0.25, MeOH)
PKA:8.67±0.20(Predicted)
PSA：113.68000
Density:1.5 g/cm³
LogP:0.20930

4836-13-9 Relevant articles

Towards Zwitterionic Oligonucleotides with Improved Properties: the NAA/LNA-Gapmer Approach

Wojtyniak, Melissa,Schmidtgall, Boris,Kirsch, Philine,Ducho, Christian

, p. 3234 - 3243 (2020/09/01)

Oligonucleotides (ON) are promising ther...

A new and convenient approach for the preparation of β-cyanoethyl protected trinucleotide phosphoramidites

Janczyk, Matthaeus,Appel, Bettina,Springstubbe, Danilo,Fritz, Hans-Joachim,Mueller, Sabine

supporting information; experimental part, p. 1510 - 1513 (2012/03/22)

Herein we report a convenient approach f...

Pyrimidine-purine and pyrimidine heterodinucleosides synthesis containing a triazole linkage

Lucas,Elchinger,Faugeras,Zerrouki

scheme or table, p. 168 - 177 (2011/08/02)

This article describes a synthetic route...

Chelation-controlled regioselective alkylation of pyrimidine 2′-deoxynucleosides

Lucas,Teste,Zerrouki,Champavier,Guilloton

scheme or table, p. 199 - 207 (2010/03/23)

Protection-deprotection steps, which are...

4836-13-9 Process route

: 93-97-0
benzoic acid anhydride

: 951-77-9
2'-Deoxycytidine

: 4836-13-9
N₄-benzoyl-2'-deoxycytidine

Conditions

Conditions	Yield
In methanol; for 10h; Heating;	86%
In ethanol; for 2h; Heating;	85%
With N-ethyl-N,N-diisopropylamine; In pyridine; for 0.0347222h; microwave irradiation;	84%
With N-ethyl-N,N-diisopropylamine; In pyridine; Microwave irradiation;	82%

: 98-88-4
benzoyl chloride

: 951-77-9
2'-Deoxycytidine

: 4836-13-9
N₄-benzoyl-2'-deoxycytidine

Conditions

Conditions	Yield
With pyridine; chloro-trimethyl-silane;	87%
2'-Deoxycytidine; With pyridine; chloro-trimethyl-silane; at 0 ℃; for 0.5h; benzoyl chloride; at 20 ℃; for 2h; With ammonium hydroxide; at 0 ℃; for 0.5h;	86%
With pyridine; sodium hydroxide; Yield given. Multistep reaction; 1.) 3 h, room temp., 2.) THF, MeOH, H₂O, 15 min, 0 deg C;
With pyridine; Me₃SiBr; at 20 ℃;
2'-Deoxycytidine; With pyridine; chloro-trimethyl-silane; for 0.5h; Cooling with ice; benzoyl chloride; at 20 ℃; for 2h;

4836-13-9 Upstream products

3992-42-5
2'-deoxycytidine monohydrochloride
98-88-4
benzoyl chloride
67219-55-0
4-N-Benzoyl-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)cytidine
13089-48-0
N₄-benzoylcytidine

4836-13-9 Downstream products

69075-27-0
4-N-benzoyl-5'-O-pixyl-2'-deoxycytidine
105862-10-0
5'-O-dimethoxytrityl-N⁴-benzoyl-2'-deoxycytidine
51549-36-1
N-(1-((2R,4S,5R)-5-(((tert-butyldimethylsilyl)oxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide
51549-38-3
N⁴-benzoyl-O^3',O^5'-bis(tert-butyldimethylsilyl)-2'-deoxycytidine

Product Classification

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4836-13-9

Product Details;

Best Price 4836-13-9 N-Benzoyl-2'-deoxy-cytidine Good Supplier In Chi

4836-13-9 Relevant articles

Towards Zwitterionic Oligonucleotides with Improved Properties: the NAA/LNA-Gapmer Approach

Wojtyniak, Melissa,Schmidtgall, Boris,Kirsch, Philine,Ducho, Christian

, p. 3234 - 3243 (2020/09/01)

A new and convenient approach for the preparation of β-cyanoethyl protected trinucleotide phosphoramidites

Janczyk, Matthaeus,Appel, Bettina,Springstubbe, Danilo,Fritz, Hans-Joachim,Mueller, Sabine

supporting information; experimental part, p. 1510 - 1513 (2012/03/22)

Pyrimidine-purine and pyrimidine heterodinucleosides synthesis containing a triazole linkage

Lucas,Elchinger,Faugeras,Zerrouki

scheme or table, p. 168 - 177 (2011/08/02)

Chelation-controlled regioselective alkylation of pyrimidine 2′-deoxynucleosides

Lucas,Teste,Zerrouki,Champavier,Guilloton

scheme or table, p. 199 - 207 (2010/03/23)

4836-13-9 Process route

4836-13-9 Upstream products

4836-13-9 Downstream products

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