What is the 2-Amino-6-chloropurine-9-riboside?

2-Amino-6-chloropurine-9-riboside is colourless crystalline solid, while it's Molecular Formula is C10H12ClN5O4. colourless crystalline solid 6-Substituted purines; a novel class of inhibitors of endogenous protein degradation

What is the CAS number for 2-Amino-6-chloropurine-9-riboside?

The CAS number of 2-Amino-6-chloropurine-9-riboside is 2004-07-1.

What is the 2-Amino-6-chloropurine-9-riboside?

2-Amino-6-chloropurine-9-riboside is colourless crystalline solid, while it's Molecular Formula is C10H12ClN5O4. colourless crystalline solid 6-Substituted purines; a novel class of inhibitors of endogenous protein degradation

What is the CAS number for 2-Amino-6-chloropurine-9-riboside?

The CAS number of 2-Amino-6-chloropurine-9-riboside is 2004-07-1.

Product Classification

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2004-07-1

Product Name：2-Amino-6-chloropurine-9-riboside
Molecular Formula：C₁₀H₁₂ClN₅O₄
Purity：99%
Molecular Weight：301.689

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Product Details;

CasNo： 2004-07-1

Molecular Formula： C₁₀H₁₂ClN₅O₄

Appearance： colourless crystalline solid

Reasoble Price High Purity 2-Amino-6-chloropurine-9-riboside 2004-07-1 Good Producer

Molecular Formula:C10H12ClN5O4
Molecular Weight:301.689
Appearance/Colour:colourless crystalline solid
Vapor Pressure:2.3E-22mmHg at 25°C
Melting Point:165-167 °C (dec.)(lit.)
Refractive Index:-38 ° (C=0.1, H2O)
Boiling Point:729.9 °C at 760 mmHg
PKA:13.05±0.70(Predicted)
Flash Point:395.2 °C
PSA：139.54000
Density:2.19 g/cm³
LogP:-0.74540

2-Amino-6-chloropurine-9-riboside(Cas 2004-07-1) Usage

Chemical Properties	Colourless Crystalline Solid
Uses	6-Substituted purines; a novel class of inhibitors of endogenous protein degradation

InChI:InChI=1/C10H12ClN5O4/c11-7-4-8(15-10(12)14-7)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)

2004-07-1 Relevant articles

Reaction of O6-methylguanosine with nitrite in the presence of carboxylic acid: Synthesis of the purin-2-yl carboxylate

Maruyama, Tokumi,Moriwaka, Nobuyasu,Demizu, Yosuke,Ohtsuka, Masami

, p. 8225 - 8228 (2005)

O6-Methylguanosine derivative was treate...

-

Kikugawa,K. et al.

, p. 387 - 390 (1972)

Intermediate for synthesizing 2-chloroadenosine, synthesis process of intermediate and synthesis process of 2-chloroadenosine

-

Paragraph 0051-0052; 0057-0059; 0060-0068, (2021/01/25)

The invention relates to the technical f...

2-Substituted α,β-Methylene-ADP Derivatives: Potent Competitive Ecto-5′-nucleotidase (CD73) Inhibitors with Variable Binding Modes

Bhattarai, Sanjay,Pippel, Jan,Scaletti, Emma,Idris, Riham,Freundlieb, Marianne,Rolshoven, Georg,Renn, Christian,Lee, Sang-Yong,Abdelrahman, Aliaa,Zimmermann, Herbert,El-Tayeb, Ali,Müller, Christa E.,Str?ter, Norbert

supporting information, p. 2941 - 2957 (2020/04/10)

CD73 inhibitors are promising drugs for ...

Synthesis of novel 6-substituted amino-9-(β-D-ribofuranosyl)purine analogs and their bioactivities on human epithelial cancer cells

Tuncbilek, Meral,Kucukdumlu, Asl?gul,Guven, Ebru Bilget,Altiparmak, Duygu,Cetin-Atalay, Rengul

, p. 235 - 239 (2018/02/15)

New nucleoside derivatives with nitrogen...

Base-modified GDP-mannose derivatives and their substrate activity towards a yeast mannosyltransferase

Collier, Alice,Wagner, Gerd K.

, p. 91 - 96 (2017/10/30)

We have previously developed a new class...

2004-07-1 Process route

: 81100-62-1
7-methylguanosine hydroiodide

: 10310-21-1
2-Amino-6-chloropurin

: 2004-07-1
2-Amino-6-chloropurine riboside

: 578-76-7
7-methylguanine

Conditions

Conditions	Yield
With recombinant purine nucleoside phosphorylase from Aeromonas hydrophila; at 20 ℃; pH=7.5; regioselective reaction; aq. phosphate buffer; Enzymatic reaction;	93%

: 16321-99-6
2-amino-6-chloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)purine

: 2004-07-1
2-Amino-6-chloropurine riboside

Conditions

Conditions	Yield
With ammonia; at 20 ℃;	93%
With methanol; sodium methylate; at 20 ℃; for 24h;	80%
With lipase; In aq. phosphate buffer; acetone; at 60 ℃; for 192h; pH=8; Enzymatic reaction;	55%
With ammonia; In methanol;
With ammonia; In methanol; at 20 ℃; for 16h;
With ammonia; In methanol; at 20 ℃;

2004-07-1 Upstream products

133519-47-8
2-amino-6-chloro-9-<3,5-bis-O-(tert-butyldimethylsilyl)-β-D-ribofuranosyl>purine
16321-99-6
2-amino-6-chloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)purine
67-56-1
methanol
3387-63-1
2-amino-6-chloro-9-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)purine

2004-07-1 Downstream products

102830-41-1
O⁶-(2-hydroxy-2-phenylethyl)guanosine
102830-40-0
O⁶-(2-hydroxy-2-phenylethyl)guanosine
102830-38-6
O⁶-(2-hydroxy-1-phenylethyl)guanosine
102830-39-7
O⁶-(2-hydroxy-12-phenylethyl)guanosine

Product Classification

Contact us

2004-07-1

Product Details;

Reasoble Price High Purity 2-Amino-6-chloropurine-9-riboside 2004-07-1 Good Producer

2-Amino-6-chloropurine-9-riboside(Cas 2004-07-1) Usage

2004-07-1 Relevant articles

Reaction of O6-methylguanosine with nitrite in the presence of carboxylic acid: Synthesis of the purin-2-yl carboxylate

Maruyama, Tokumi,Moriwaka, Nobuyasu,Demizu, Yosuke,Ohtsuka, Masami

, p. 8225 - 8228 (2005)

-

Kikugawa,K. et al.

, p. 387 - 390 (1972)

Intermediate for synthesizing 2-chloroadenosine, synthesis process of intermediate and synthesis process of 2-chloroadenosine

-

Paragraph 0051-0052; 0057-0059; 0060-0068, (2021/01/25)

2-Substituted α,β-Methylene-ADP Derivatives: Potent Competitive Ecto-5′-nucleotidase (CD73) Inhibitors with Variable Binding Modes

Bhattarai, Sanjay,Pippel, Jan,Scaletti, Emma,Idris, Riham,Freundlieb, Marianne,Rolshoven, Georg,Renn, Christian,Lee, Sang-Yong,Abdelrahman, Aliaa,Zimmermann, Herbert,El-Tayeb, Ali,Müller, Christa E.,Str?ter, Norbert

supporting information, p. 2941 - 2957 (2020/04/10)

Synthesis of novel 6-substituted amino-9-(β-D-ribofuranosyl)purine analogs and their bioactivities on human epithelial cancer cells

Tuncbilek, Meral,Kucukdumlu, Asl?gul,Guven, Ebru Bilget,Altiparmak, Duygu,Cetin-Atalay, Rengul

, p. 235 - 239 (2018/02/15)

Base-modified GDP-mannose derivatives and their substrate activity towards a yeast mannosyltransferase

Collier, Alice,Wagner, Gerd K.

, p. 91 - 96 (2017/10/30)

2004-07-1 Process route

2004-07-1 Upstream products

2004-07-1 Downstream products

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