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84558-94-1

  • Product Name:5-PROPYNYL-2'-DEOXYURIDINE
  • Molecular Formula:C12H14 N2 O5
  • Purity:99%
  • Molecular Weight:266.254
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Product Details;

CasNo: 84558-94-1

Molecular Formula: C12H14 N2 O5

High Quality For Sale Low Price 5-PROPYNYL-2'-DEOXYURIDINE 84558-94-1

  • Molecular Formula:C12H14N2O5
  • Molecular Weight:266.254
  • PKA:8.42±0.10(Predicted) 
  • PSA:104.55000 
  • Density:1.50±0.1 g/cm3(Predicted) 
  • LogP:-1.45130 

84558-94-1 Relevant articles

2′-De-oxy-5-propynyluridine: A nucleoside with two conformations in the asymmetric unit

Budow, Simone,Eickmeier, Henning,Reuter, Hans,Seela, Frank

, p. o645-o648 (2009)

The title compound, 1-(2-de-oxy-Β-d-eryt...

Design and studies of novel 5-substituted alkynylpyrimidine nucleosides as potent inhibitors of mycobacteria

Rai, Dinesh,Johar, Monika,Manning, Tracey,Agrawal,Kunimoto, Dennis Y.,Kumar, Rakesh

, p. 7012 - 7017 (2007/10/03)

We herein report a new category of 5-sub...

Pyrrolo-dC and pyrrolo-C: Fluorescent analogs of cytidine and 2′-deoxycytidine for the study of oligonucleotides

Berry, David A.,Jung, Kee-Yong,Wise, Dean S.,Sercel, Anthony D.,Pearson, William H.,Mackie, Hugh,Randolph, John B.,Somers, Robert L.

, p. 2457 - 2461 (2007/10/03)

Pyrrolo-dC (1a, 6-methyl-3-(2-deoxy-β-D-...

Rapid methylation of terminal acetylenes by the Stille coupling of methyl iodide with alkynyltributylstannanes: A general protocol potentially useful for the synthesis of short-lived 11CH3-labeled PET tracers with a 1-propynyl group

Hosoya, Takamitsu,Wakao, Masahiro,Kondo, Yurie,Doi, Hisashi,Suzuki, Masaaki

, p. 24 - 27 (2007/10/03)

The Pd(0)-mediated rapid coupling (trapp...

84558-94-1 Process route

5-Iodo-2'-deoxyuridine
54-42-2,162239-35-2

5-Iodo-2'-deoxyuridine

prop-1-yne
74-99-7

prop-1-yne

5-(1-propynyl)-2'-deoxyuridine
84558-94-1

5-(1-propynyl)-2'-deoxyuridine

3-(β-D-2-deoxyribofuranosyl)-6-methylfuro[2,3-d]pyrimidin-2-one
383897-60-7

3-(β-D-2-deoxyribofuranosyl)-6-methylfuro[2,3-d]pyrimidin-2-one

Conditions
Conditions Yield
With copper(l) iodide; triethylamine; tetrakis(triphenylphosphine) palladium(0); In N,N-dimethyl-formamide; at 55 - 60 ℃; for 18h;
50%
45%
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); In N,N-dimethyl-formamide;
5-Iodo-2'-deoxyuridine
54-42-2,162239-35-2

5-Iodo-2'-deoxyuridine

prop-1-yne
74-99-7

prop-1-yne

5-(1-propynyl)-2'-deoxyuridine
84558-94-1

5-(1-propynyl)-2'-deoxyuridine

Conditions
Conditions Yield
With copper(l) iodide; triethylamine; tetrakis(triphenylphosphine) palladium(0); In N,N-dimethyl-formamide;
65%
Pd-catalysis; Yield given;
With palladium;

84558-94-1 Upstream products

  • 54-42-2
    54-42-2

    5-Iodo-2'-deoxyuridine

  • 74-99-7
    74-99-7

    prop-1-yne

  • 84558-92-9
    84558-92-9

    5-propynyl-3',5'-di-O-p-toluyl-2'-deoxyuridine

  • 74-88-4
    74-88-4

    methyl iodide

84558-94-1 Downstream products

  • 383897-60-7
    383897-60-7

    3-(β-D-2-deoxyribofuranosyl)-6-methylfuro[2,3-d]pyrimidin-2-one

  • 644962-92-5
    644962-92-5

    Diisopropyl-phosphoramidous acid (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(6-methyl-2-oxo-2,7-dihydro-pyrrolo[2,3-d]pyrimidin-3-yl)-tetrahydro-furan-3-yl ester 2-cyano-ethyl ester

  • 644962-87-8
    644962-87-8

    3-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-6-methyl-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-2-one

  • 644962-78-7
    644962-78-7

    3-{5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-6-methyl-3H-furo[2,3-d]pyrimidin-2-one

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