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2140-61-6

  • Product Name:5-METHYLCYTIDINE
  • Molecular Formula:C10H15N3O5
  • Purity:99%
  • Molecular Weight:257.246
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Product Details;

CasNo: 2140-61-6

Molecular Formula: C10H15N3O5

Appearance: Light Yellow Crystals

Factory Sells Low Price 5-METHYLCYTIDINE 2140-61-6

  • Molecular Formula:C10H15N3O5
  • Molecular Weight:257.246
  • Appearance/Colour:Light Yellow Crystals 
  • Vapor Pressure:8.5E-14mmHg at 25°C 
  • Melting Point:212-215 °C (dec.)(lit.) 
  • Refractive Index:15 ° (C=2, H2O) 
  • Boiling Point:537.5 °C at 760 mmHg 
  • PKA:pK1:4.21 (25°C) 
  • Flash Point:278.9 °C 
  • PSA:130.83000 
  • Density:1.79 g/cm3 
  • LogP:-1.67340 

5-METHYLCYTIDINE(Cas 2140-61-6) Usage

Chemical Properties

White powder

Uses

5-Methylcytidine is a derivative of Cytidine (C998300), found in ribonucleic acids of animals, plants and bacteria. 5-Methylcytidine is a nucleoside found in liver emulsion that can inhibit the growth of spontaneous tumors of mammary gland origin in mice. 5-Methylcytidine is one of many nucleosides that can be used as biomedical marker using liquid chromatography and ion trap mass spectrometry coupling.

General Description

5-Methylcytidine is a component of RNA in Escherichia coli. It is present in the RNA of plant, animal and bacterial origin. It is one of the C derivative present in transfer RNA (tRNA).

Biochem/physiol Actions

5-Methylcytidine is an alkylated pyrimidine plays an important role enhancing the stacking in A- and B- helices of nucleic acid, results in increase of the melting temperature and improves thermal stability leading to structural stabilization.

InChI:InChI=1/C10H15N3O5/c1-4-2-13(10(17)12-8(4)11)9-7(16)6(15)5(3-14)18-9/h2,5-7,9,14-16H,3H2,1H3,(H2,11,12,17)

2140-61-6 Relevant articles

Identification of Flavin Mononucleotide as a Cell-Active Artificial N6-Methyladenosine RNA Demethylase

Xie, Li-Jun,Yang, Xiao-Ti,Wang, Rui-Li,Cheng, Hou-Ping,Li, Zhi-Yan,Liu, Li,Mao, Lanqun,Wang, Ming,Cheng, Liang

supporting information, p. 5028 - 5032 (2019/03/17)

N6-Methyladenosine (m6A) represents a co...

SYNTHESIS AND STRUCTURE OF HIGH POTENCY RNA THERAPEUTICS

-

, (2019/01/15)

This invention provides expressible poly...

Oligonucleotides comprising a modified or non-natural nucleobase

-

, (2008/06/13)

One aspect of the present invention rela...

Anti-HCV nucleoside derivatives

-

, (2008/06/13)

The present invention comprises novel an...

2140-61-6 Process route

N<sup>4</sup>,5-dimethylcytidine
117862-70-1

N4,5-dimethylcytidine

5-methylcytidine
2140-61-6

5-methylcytidine

Conditions
Conditions Yield
With manganese(IV) oxide; C17H20N4O9P(1-)*Na(1+); oxygen; In water; acetonitrile; at 20 ℃; for 7h; under 760.051 Torr; chemoselective reaction; Irradiation;
70%
4-methoxy-5-methyl-1-(tri-<i>O</i>-benzoyl-β-<i>D</i>-ribofuranosyl)-1<i>H</i>-pyrimidin-2-one
7323-83-3

4-methoxy-5-methyl-1-(tri-O-benzoyl-β-D-ribofuranosyl)-1H-pyrimidin-2-one

5-methylcytidine
2140-61-6

5-methylcytidine

Conditions
Conditions Yield
With ammonia; In methanol; at 100 ℃; for 21h;
67%

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    5-hydroxymethylcytosine

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