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873107-98-3

  • Product Name:5-Iodo-2-(trifluoromethyl)pyridine
  • Molecular Formula:C6H3F3IN
  • Purity:99%
  • Molecular Weight:272.996
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Product Details;

CasNo: 873107-98-3

Molecular Formula: C6H3F3IN

Top Purity 5-Iodo-2-(trifluoromethyl)pyridine 873107-98-3 In Medicine

  • Molecular Formula:C6H3F3IN
  • Molecular Weight:272.996
  • Vapor Pressure:0.39mmHg at 25°C 
  • Boiling Point:203.71°C at 760 mmHg 
  • PKA:-1.47±0.22(Predicted) 
  • Flash Point:77.002°C 
  • PSA:12.89000 
  • Density:1.975g/cm3 
  • LogP:2.70500 

5-IODO-2-(TRIFLUOROMETHYL)PYRIDINE(Cas 873107-98-3) Usage

Uses

5-Iodo-2-(trifluoromethyl)pyridine is a useful reactant for metal-catalyzed organic reactions.

InChI:InChI=1/C6H3F3IN/c7-6(8,9)5-2-1-4(10)3-11-5/h1-3H

873107-98-3 Relevant articles

Rapid Assembly of Saturated Nitrogen Heterocycles in One-Pot: Diazo-Heterocycle “Stitching” by N–H Insertion and Cyclization

Boddy, Alexander J.,Affron, Dominic P.,Cordier, Christopher J.,Rivers, Emma L.,Spivey, Alan C.,Bull, James A.

supporting information, p. 1458 - 1462 (2019/01/04)

Methods that provide rapid access to new...

PYRROLOPYRIMIDINE DERIVATIVES AS NR2B NMDA RECEPTOR ANTAGONISTS

-

Paragraph 0347, (2016/04/09)

Disclosed are chemical entities of formu...

DIFLUOROETHYLPYRIDINE DERIVATIVES AS NR2B NMDA RECEPTOR ANTAGONISTS

-

Paragraph 0251, (2016/02/16)

Disclosed are chemical entities of formu...

Nickel-Catalyzed Asymmetric Reductive Cross-Coupling between Heteroaryl Iodides and α-Chloronitriles

Kadunce, Nathaniel T.,Reisman, Sarah E.

supporting information, p. 10480 - 10483 (2015/09/28)

A Ni-catalyzed asymmetric reductive cros...

873107-98-3 Process route

6-(trifluoromethyl)pyridin-3-amine
106877-33-2

6-(trifluoromethyl)pyridin-3-amine

5-iodo-2-(trifluoromethyl)pyridine
873107-98-3

5-iodo-2-(trifluoromethyl)pyridine

Conditions
Conditions Yield
6-(trifluoromethyl)pyridin-3-amine; With hydrogenchloride; sodium nitrite; In water; at -5 - 5 ℃; for 0.166667h;
With potassium iodide; In water; at -5 - 10 ℃;
87%
6-(trifluoromethyl)pyridin-3-amine; With hydrogenchloride; sodium nitrite; In water; at -5 - 5 ℃; for 0.166667h;
With potassium iodide; In water; at -5 - 20 ℃;
87%
6-(trifluoromethyl)pyridin-3-amine; With tetrafluoroboric acid; sodium nitrite; In water; at 0 - 20 ℃; for 0.25h;
With potassium iodide; In water; for 0.666667h;
5-bromo-2(trifluoromethyl)pyridine
436799-32-5

5-bromo-2(trifluoromethyl)pyridine

5-iodo-2-(trifluoromethyl)pyridine
873107-98-3

5-iodo-2-(trifluoromethyl)pyridine

Conditions
Conditions Yield
With copper(l) iodide; sodium iodide; N,N`-dimethylethylenediamine; In 1,4-dioxane; at 110 ℃; for 24h;
82%
With copper(l) iodide; sodium iodide; N,N`-dimethylethylenediamine; In 1,3-dioxane; at 110 ℃; for 24h; Inert atmosphere;

873107-98-3 Upstream products

  • 106877-33-2
    106877-33-2

    6-(trifluoromethyl)pyridin-3-amine

  • 436799-32-5
    436799-32-5

    5-bromo-2(trifluoromethyl)pyridine

873107-98-3 Downstream products

  • 1425511-71-2
    1425511-71-2

    3,4-bis(benzyloxy)-6-{[6-(trifluoromethyl)pyridin-3-yl]ethynyl}pyridazine

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