Contact us

Tel:021-6710 8196

Phone:191 2194 8821

Website:https://www.xhmedi.com

Email: sales@xhmedic.com

Address:Room 306, Building A, 1888 Wangyuan Road, Fengxian District, Shanghai,China

90481-33-7

  • Product Name:N-BOC-(3S,4S)-3,4-PYRROLIDINEDIOL
  • Molecular Formula:C9H17NO4
  • Purity:99%
  • Molecular Weight:203.238
Inquiry

Product Details;

CasNo: 90481-33-7

Molecular Formula: C9H17NO4

High Purity Low Price N-BOC-(3S,4S)-3,4-PYRROLIDINEDIOL 90481-33-7

  • Molecular Formula:C9H17NO4
  • Molecular Weight:203.238
  • Vapor Pressure:0.00011mmHg at 25°C 
  • Melting Point:163-164℃ (ethyl acetate ) 
  • PSA:70.00000 
  • LogP:-0.10320 

N-BOC-(3S,4S)-3,4-PYRROLIDINEDIOL(Cas 90481-33-7) Usage

N-BOC-(3S,4S)-3,4-Pyrrolidinediol is a synthetic compound that has been developed for use as a chiral building block in organic synthesis. It is a derivative of pyrrolidine, a five-membered nitrogen-containing heterocycle that is commonly found in natural products and pharmaceuticals. The N-BOC (tert-butyloxycarbonyl) protecting group is used to prevent unwanted reactions during chemical synthesis, allowing for selective modification of the pyrrolidine ring. The (3S,4S) stereochemistry refers to the orientation of the two substituents on the pyrrolidine ring, which can have a significant impact on the properties and activity of the final product. N-BOC-(3S,4S)-3,4-Pyrrolidinediol is widely used in the pharmaceutical industry for the synthesis of a variety of biologically active compounds, including antiviral agents, antibiotics, and anticancer drugs.

InChI:InChI=1/C9H17NO4/c1-9(2,3)14-8(13)10-4-6(11)7(12)5-10/h6-7,11-12H,4-5H2,1-3H3/t6-,7-/m0/s1

90481-33-7 Relevant articles

Selective Isomerization via Transient Thermodynamic Control: Dynamic Epimerization of trans to cis Diols

Macmillan, David W. C.,Oswood, Christian J.

supporting information, p. 93 - 98 (2022/01/03)

Traditional approaches to stereoselectiv...

Compound JK-03M having higher protein kinase G inhibitory activity or pharmaceutically acceptable salt thereof and preparation method thereof

-

Paragraph 0093; 0118; 0135-0137, (2018/11/03)

The invention discloses a compound which...

Compounds with higher PKG (protein kinase G) inhibitory activity and preparation method of compounds

-

Paragraph 0160; 0161; 0162; 0163; 0164; 0165, (2016/10/08)

The invention discloses compounds which ...

COMPOUND HAVING HIGHER INHIBITION OF PROTEIN KINASE G ACTIVITY AND PREPARATION METHOD THEREFOR

-

Paragraph 0075; 0076, (2016/12/12)

Disclosed are a compound of Formula I ha...

90481-33-7 Process route

di-<i>tert</i>-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

(3S,4S)-pyrrolidine-3,4-diol
90481-32-6

(3S,4S)-pyrrolidine-3,4-diol

S,S-3,4-dihydroxypyrrolidine-1-carboxylic acid tert-butyl ester
150986-62-2,90481-33-7,186393-22-6

S,S-3,4-dihydroxypyrrolidine-1-carboxylic acid tert-butyl ester

Conditions
Conditions Yield
 
86%
With sodium hydrogencarbonate; In 1,4-dioxane; water; at 20 ℃; for 2h;
85%
With sodium hydrogencarbonate; In 1,4-dioxane; water; at 20 ℃; for 2h;
84.6%
With sodium hydrogencarbonate; In 1,4-dioxane; water; at 20 ℃; for 2h;
84.6%
With sodium hydrogencarbonate; In 1,4-dioxane; water; at 20 ℃; for 2h;
84.6%
With potassium carbonate; acetic acid; In methanol; chloroform;
75%
With triethylamine; In dichloromethane; for 3h;
 
1-tert-butoxycarbonyl-3,4-epoxypyrrolidine
114214-49-2

1-tert-butoxycarbonyl-3,4-epoxypyrrolidine

S,S-3,4-dihydroxypyrrolidine-1-carboxylic acid tert-butyl ester
150986-62-2,90481-33-7,186393-22-6

S,S-3,4-dihydroxypyrrolidine-1-carboxylic acid tert-butyl ester

Conditions
Conditions Yield
With water; In acetonitrile; at 23 ℃; for 24h; enantioselective reaction;
91%

90481-33-7 Upstream products

  • 24424-99-5
    24424-99-5

    di-tert-butyl dicarbonate

  • 90481-32-6
    90481-32-6

    (3S,4S)-pyrrolidine-3,4-diol

  • 90365-74-5
    90365-74-5

    (3S,4S)-(+)-1-benzyl-3,4-pyrrolidinediol

  • 762-75-4
    762-75-4

    tert-butyl formate

90481-33-7 Downstream products

  • 722545-09-7
    722545-09-7

    (+)-(3R,4R)-1-tert-butoxycarbonyl-3,4-bis(phenylsulfanyl)pyrrolidine

  • 926913-07-7
    926913-07-7

    (3S,4S)-1-N-tert-butyloxycarbonyl-3-(4,4'-dimethoxytrityloxy)-4-hydroxypyrrolidine

  • 557-40-4
    557-40-4

    Allyl ether

  • 1374429-77-2
    1374429-77-2

    (3R,4S)-tert-butyl 3-azido-4-(bis(4-methoxyphenyl)(phenyl)methoxy)pyrrolidine-1-carboxylate

ShoppingCart

Clear Inquiry