What is the 5-Methyl-2'-deoxycytidine?

5-Methyl-2'-deoxycytidine is white solid, while it's Molecular Formula is C10H15N3O4. white solid A Cytidine (C998300) analog and also an isostere of Thymidine (T412000).

What is the CAS number for 5-Methyl-2'-deoxycytidine?

The CAS number of 5-Methyl-2'-deoxycytidine is 838-07-3.

What is 5-Methyl-2'-deoxycytidine (838-07-3) used for?

5-Methyl-2'-deoxycytidine is a nucleoside analogue that inhibits the synthesis of DNA. 5-Methyl-2'-deoxycytidine prevents methylation of guanine, which disrupts the binding of guanine nucleotide-binding proteins to the dna template and prevents polymerase chain reactions. 2'-Deoxy-5-methylcytidine is also a methyltransferase inhibitor, which means it blocks the enzyme responsible for adding methyl groups to cytosine molecules.

What is the 5-Methyl-2'-deoxycytidine?

5-Methyl-2'-deoxycytidine is white solid, while it's Molecular Formula is C10H15N3O4. white solid A Cytidine (C998300) analog and also an isostere of Thymidine (T412000).

What is the CAS number for 5-Methyl-2'-deoxycytidine?

The CAS number of 5-Methyl-2'-deoxycytidine is 838-07-3.

What is 5-Methyl-2'-deoxycytidine (838-07-3) used for?

5-Methyl-2'-deoxycytidine is a nucleoside analogue that inhibits the synthesis of DNA. 5-Methyl-2'-deoxycytidine prevents methylation of guanine, which disrupts the binding of guanine nucleotide-binding proteins to the dna template and prevents polymerase chain reactions. 2'-Deoxy-5-methylcytidine is also a methyltransferase inhibitor, which means it blocks the enzyme responsible for adding methyl groups to cytosine molecules.

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838-07-3

Product Name：5-Methyl-2'-deoxycytidine
Molecular Formula：C₁₀H₁₅N₃O₄
Purity：99%
Molecular Weight：241.247

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Product Details;

CasNo： 838-07-3

Molecular Formula： C₁₀H₁₅N₃O₄

Appearance： white solid

Hot sale Price High Purity 5-Methyl-2'-deoxycytidine 838-07-3 In Bulk supply

Molecular Formula:C10H15N3O4
Molecular Weight:241.247
Appearance/Colour:white solid
Melting Point:217-219 °C(lit.)
Refractive Index:44 ° (C=1.4, H2O)
Boiling Point:492.8 °C at 760 mmHg
PKA:pK1:4.33 (25°C)
Flash Point:251.9 °C
PSA：110.60000
Density:1.64 g/cm³
LogP:-0.64420

838-07-3 Relevant articles

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Dekker,Elmore

, p. 2864,2867 (1951)

DNA methylation by dimethyl sulfoxide and methionine sulfoxide triggered by hydroxyl radical and implications for epigenetic modifications

Kawai, Kazuaki,Li, Yun-Shan,Song, Ming-Fen,Kasai, Hiroshi

, p. 260 - 265 (2010)

In this Letter, we demonstrate the forma...

An efficient PyAOP-based C4-amination method for direct access of oxidized 5MedC derivatives

Zheng, Xiu-An,Huang, Hua-Shan,Kong, Rui,Chen, Wei-Jie,Gong, Shan-Shan,Sun, Qi

, p. 7095 - 7101 (2018/10/31)

In the past decade, synthetic oxidized 5...

Quantification of the sixth DNA base hydroxymethylcytosine in the brain

Muenzel, Martin,Globisch, Daniel,Brueckl, Tobias,Wagner, Mirko,Welzmiller, Veronika,Michalakis, Stylianos,Mueller, Markus,Biel, Martin,Carell, Thomas

supporting information; experimental part, p. 5375 - 5377 (2010/10/18)

Mind over matter: LC-MS has allowed the ...

Modulation of DNA triplex stability through nucleobase modifications

Ganesh, Krishna N.,Rajeev, Kallanthottathil G.,Pallan, Pradeep S.,Rana, Vipul S.,Barawkar, Dinesh A.,Kumar, Vaijayanti A.

, p. 1271 - 1278 (2007/10/03)

Spermine conjugation at N4 of 5-Me-dC in...

838-07-3 Process route

: 50-89-5,28854-96-8,3545-96-8,50-88-4
thymidine

: 838-07-3
5-methyldeoxycytidine

Conditions

Conditions	Yield
thymidine; With 1,8-diazabicyclo[5.4.0]undec-7-ene; ((3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V); In N,N-dimethyl-formamide; at 20 ℃; for 0.0166667h; With ammonium hydroxide; In N,N-dimethyl-formamide; at 20 ℃; for 2h; Reagent/catalyst; Time;	92%
Multi-step reaction with 3 steps 1: Et₃N / CH₂Cl₂ / 0.5 h 2: acetonitrile / 2 h / Ambient temperature 3: NH₃ / tetrahydrofuran / 72 h / 70 °C With ammonia; triethylamine; In tetrahydrofuran; dichloromethane; acetonitrile;
Multi-step reaction with 3 steps 1: pyridine 2: aqueous pyridine; P₂S₅ 3: ethanol; NH₃ With pyridine; tetraphosphorus decasulfide; ethanol; ammonia;

: 115652-25-0
5-methyl-1-(3,5-di-O-acetyl-2-deoxy-β-D-erythro-pentofuranosyl)cytidine

: 838-07-3
5-methyldeoxycytidine

Conditions

Conditions	Yield
With ammonia; at 25 ℃;	85%
With ammonia; In methanol; at 25 ℃; for 24h; Yield given;

838-07-3 Upstream products

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thymidine